Metacognition in Semantic Dementia: Comparison With Alzheimer's Disease (META-DEM)

  • End date
    Jul 24, 2023
  • participants needed
  • sponsor
    University Hospital, Grenoble
Updated on 24 May 2022
mini-mental state examination
alzheimer's disease
Accepts healthy volunteers


This study aims at exploring patients' ability to monitor their own memory performance depending on their primary deficit and the type of memory involved in the criterion task. The goal is to evaluate if semantic dementia (SD) and Alzheimer's disease (AD) differently affect patients' awareness of their memory abilities.


Patients who will give their informed non-opposition will be included. Participants will undergo 6 metacognitive tasks in which they will be tested on newly learnt information (i.e., episodic memory) or prior knowledge (i.e., semantic memory) and asked to evaluate their performance either prior or after the test. Correlation between their evaluation and their actual performance will be measured. Performance and correlations will be compared across groups.

Condition Semantic Dementia, Alzheimer Disease, Healthy
Treatment Metacognition tests
Clinical Study IdentifierNCT04597827
SponsorUniversity Hospital, Grenoble
Last Modified on24 May 2022


Yes No Not Sure

Inclusion Criteria

native French-speakers
normal or corrected-to-normal vision
for patients ONLY : doctor-approved diagnosis of semantic dementia or Alzheimer's disease
for healthy participants ONLY: score above 27 on the MMSE
non-opposition in participation

Exclusion Criteria

other neurological/ psychiatric disorder, or cognitive disorder that might affect general cognition
drug or alcohol abuse
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact


Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider


Browse trials for

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 



Reply by • Private

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note