Personalized Treatment for Patients With Premature Ventricular Beats

  • End date
    Jul 31, 2040
  • participants needed
  • sponsor
    Oslo University Hospital
Updated on 26 January 2021


Frequent premature ventricular beats (PVBs) are common, negatively affects the quality of life for many patients, and can lead to impaired contractile function. Rule-out of structural heart disease is key in the assessment of PVBs. Cardiac MR has a high sensitivity for structural heart disease, but the diagnostic gain from this resource-demanding procedure in the work-up of patients with PVBs is unknown. There is a need to establish the role of MR in the evaluation of patients with PVBs to improve diagnostic efficacy, establish treatment strategies, and promote further research. This project will answer three key questions: 1) What is the diagnostic gain from cardiac MR in patients with PVBs? 2) Is MR the real gold standard to rule-out structural heart disease in patients with PVBs? 3) Can non-invasive heart rate parameters guide the strategy for induction of PVBs during invasive electrophysiological procedures?

Condition Premature ventricular contractions, ventricular extrasystoles
Treatment Cardiac MRI, Transthoracic Echocardiography, Coronary Angiography, Cardiopulmonary exercise testing, Holter monitoring, Invasive cardiac electrophysiological study and ablation therapy
Clinical Study IdentifierNCT04617717
SponsorOslo University Hospital
Last Modified on26 January 2021


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Inclusion Criteria

Patients referred for PVC ablation
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