A Phase 3 Multicenter, Randomized, Placebo-controlled, Double-blind Clinical Study to Evaluate the Efficacy and Safety of MK-4305 (Suvorexant) for Reducing Incidence of Delirium in Japanese Participants at High Risk of Delirium

  • participants needed
  • sponsor
    Merck Sharp & Dohme LLC
Updated on 27 January 2023


The goal of this study is to evaluate the efficacy and safety of suvorexant (MK-4305) for reducing the incidence of delirium in Japanese participants who are at high risk of delirium. The primary hypothesis is that suvorexant reduces the proportion of participants with delirium compared with placebo as assessed by the diagnostic and statistical manual of mental disorders 5th edition (DSM-5) criteria.

Condition Delirium
Treatment Placebo, Suvorexant
Clinical Study IdentifierNCT04571944
SponsorMerck Sharp & Dohme LLC
Last Modified on27 January 2023

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