Hip Arthroscopy Versus Total Hip Arthroplasty RCT

  • STATUS
    Recruiting
  • End date
    Jan 31, 2028
  • participants needed
    160
  • sponsor
    Western University, Canada
Updated on 25 March 2022
osteoarthritis
osteotomy
hip arthroplasty
hip replacement
joint reconstruction

Summary

The aim of the proposed study is to perform a comparative pilot, randomized controlled trial of hip arthroscopy versus definitive total hip arthroplasty (THA) for the treatment of early hip osteoarthritis (Tönnis Grade 1-2) in patients between the ages of 40-60 years.

Description

The purpose of this study is to conduct a randomized trial to compare hip arthroscopy to THR and estimate the long-term cost-effectiveness. Specifically, we aim to:

  1. Estimate the magnitude of the between-groups difference in the primary outcome (Hip Dysfunction and Osteoarthritis Outcome Score - HOOS);
  2. Evaluate the clinical and cost-effectiveness of early definitive THA compared to arthroscopy for early-stage hip OA at 1-year postoperative;
  3. Estimate the lifetime cost-effectiveness of arthroscopy vs THA using a Markov model; and
  4. Identify imaging and biomechanical predictors of outcomes following hip arthroscopy

Details
Condition Hip Osteoarthritis
Treatment Total Hip Arthroplasty, Hip Arthroscopy
Clinical Study IdentifierNCT04166227
SponsorWestern University, Canada
Last Modified on25 March 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Between the ages of 40-60 years at the time of surgery
Radiographic evidence of mild to moderate hip OA (Tönnis Gr 0 with MRI chondral wear, Tönnis Gr 1 and 2)
Patients must have completed ≥3 months of non-operative management with ongoing symptoms

Exclusion Criteria

Patients who are pregnant or may become pregnant around the time of surgery
Advanced OA, defined as <2 mm joint space (Tönnis Gr 3) or those with acetabular or femoral head cysts
Prior arthroplasty of the contralateral hip
Current or prior hip dysplasia (defined by a lateral centre edge angle of <20 degrees)
Acetabular protrusio or coxa profunda, making arthroscopic access unsafe/unfeasible
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