Ischemic Strokes While on NOAC - How Compliance Matters

  • End date
    Mar 31, 2024
  • participants needed
  • sponsor
    Chinese University of Hong Kong
Updated on 4 October 2022


This study is aimed to depict the epidemiological trend, aetiologies, clinical characteristics, treatment options of IS-NOAC in face of the rapidly increasing NOAC usage. Knowledge on this ischaemic stroke entity will define clinical characteristics, identify preventable causes and inform resource allocation on the evaluation modalities, reperfusion strategies and forecast future burden of IS-NOAC.


Data will be retrieved from the stroke registry of Prince of Wales Hospital which recorded all in- and out-patients with stroke or transient ischaemic attack (TIA). All consecutive adult patients with known AF who developed ischaemic stroke or TIA in 2010, 2012, 2014, 2016 and 2018 (i.e. 5 full yearly time-points) and categorize the patients according to their anticoagulation status (elaborated below) with the inclusion and exclusion criteria stated will be recruited.

All demographic data, blood results, imaging and assessment data will be retrieved from electronic patient record (CMS system) and stroke registry. All-cause mortality at 1 year will be verified via CMS system too.

Condition Stroke, Ischemic, Stroke, Acute, Stroke Syndrome, Stroke, Cardiovascular, Atherosclerosis, Ischemic Stroke
Clinical Study IdentifierNCT04607070
SponsorChinese University of Hong Kong
Last Modified on4 October 2022


Yes No Not Sure

Inclusion Criteria

Patients who were ethnic Chinese
Patients with known AF
Patient who suffered from ischaemic stroke

Exclusion Criteria

Patient who are non-ethnic Chinese
Patient who suffered from haemorrhagic stroke
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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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