The Effects of Tranexamic Acid on Joint Inflammation and Cartilage Health in Anterior Cruciate Ligament Injured Patients

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    Stanford University
Updated on 31 January 2023
tranexamic acid
reconstructive surgery
anterior cruciate ligament injury


Patients who tear their ACL are at high risk for developing arthritis (post-traumatic osteoarthritis-PTOA) just 10 years later. Joint bleeding and inflammation contribute to deterioration of joint health. This study will determine whether treatment with Tranexamic Acid (TXA), an FDA approved medication that reduces bleeding right after ACL injury and reconstructive surgery reduces inflammation and improves joint health as a new strategy to prevent or delay the onset of PTOA.

Condition Anterior Cruciate Ligament Reconstruction
Treatment placebos, Tranexamic Acid
Clinical Study IdentifierNCT03552705
SponsorStanford University
Last Modified on31 January 2023

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