Anesthesia and Cancer Study: Renal Cell Carcinoma

  • End date
    Jul 21, 2025
  • participants needed
  • sponsor
    Seoul National University Hospital
Updated on 21 March 2022


This study investigates the influence of type of anesthesia on recurrence and survival of renal cell carcinoma in patients undergoing nephrectomy. The participants will be allocated to either the group receiving the total intravenous anesthesia (TIVA) using propofol or the group receiving the inhaled anesthetics, such as sevoflurane or desflurane.


The effect of anesthesia on cancer recurrence and survival is controversial. According to some retrospective studies and preclinical studies, TIVA is suggested to be more favorable than inhalation anesthesia regarding cancer recurrence and survival after surgery. However, to our knowledge, there is no study which investigates the influence of type of anesthesia on recurrence of renal cell carcinoma after nephrectomy.

Condition Renal Cell Carcinoma
Treatment Propofol, Inhaled General Anesthetics
Clinical Study IdentifierNCT04503148
SponsorSeoul National University Hospital
Last Modified on21 March 2022


Yes No Not Sure

Inclusion Criteria

Adult patients scheduled for elective nephrectomy due to renal cell carcinoma

Exclusion Criteria

Emergency surgery
Allergies to anesthetics
Palliative surgery
Refusal to participate in the study
History of diagnosis or surgery for other cancer
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