A Study of Oral Upadacitinib Tablets to Assess Treatment Patterns Achievement of Treatment Targets and Maintenance of Response in Adult Participants With Moderate to Severe Rheumatoid Arthritis

  • STATUS
    Recruiting
  • End date
    Jan 31, 2024
  • participants needed
    1660
  • sponsor
    AbbVie
Updated on 23 November 2020
Investigator
AbbVie_Call Center
Primary Contact
BJC Health /ID# 223884 (6.8 mi away) Contact
+106 other location
remission
prednisone
glucocorticoids
stiffness

Summary

Rheumatoid Arthritis (RA) is an inflammatory disease of the joints causing pain, stiffness, swelling and loss of joint function. Despite the range of treatment options for RA steadily increasing, many patients remain sub-optimally managed, with sustained clinical remission rarely achieved. This study will assess the treatment patterns, achievement of treatment targets and maintenance of response.

Upadacitinib is a drug approved for the treatment of moderately to severely active rheumatoid arthritis. Adult participants with moderate to severe RA who have been prescribed upadacitinib by their physicians will be enrolled. Approximately, 1660 participants will be enrolled this study, worldwide.

Participants will not receive Upadacitinib as part of this study, but will be followed for response to treatment for up to 24 months.

There may be higher burden for participants in this trial compared to their standard of care. Participants will attend regular visits, every 3 months, during the course of the study at a hospital or clinic and will be asked to provide additional information by questionnaire at each visit.

Details
Clinical Study IdentifierNCT04497597
SponsorAbbVie
Last Modified on23 November 2020

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Eligibility

Yes No Not Sure

Inclusion Criteria

Is your age greater than or equal to 18 yrs?
Gender: Male or Female
Do you have any of these conditions: Rheumatoid Arthritis (Pediatric) or Rheumatoid Arthritis?
Do you have any of these conditions: Rheumatoid Arthritis or Rheumatoid Arthritis (Pediatric)?
Do you have any of these conditions: Rheumatoid Arthritis (Pediatric) or Rheumatoid Arthritis?
Confirmed diagnosis of moderate to severe active Rheumatoid Arthritis (RA)
Physician decision on patient treatment with upadacitinib must have been reached prior to and independently of recruitment in the study
Upadacitinib prescribed in accordance to the applicable approved label and local regulatory and reimbursement policies
French Participants Only: Taking oral glucocorticoids 5 mg/day of prednisone or equivalent for at least 3 months prior to study start

Exclusion Criteria

Prior treatment with Upadacitinib
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