Isolation Procedure vs. Conventional Procedure During Distal Pancreatectosplenectomy for Pancreatic Cancer

  • STATUS
    Recruiting
  • End date
    Sep 30, 2025
  • participants needed
    100
  • sponsor
    Wakayama Medical University
Updated on 26 January 2021
Investigator
Ken-ichi Okada, M.D., Ph.D.
Primary Contact
Shiga Medical University (5.6 mi away) Contact
+9 other location

Summary

In the distal pancreatectomy (including pancreatic tail resection) for invasive ductal carcinoma of the pancreas, we evaluate the usefulness of a procedure of firstly transection of splenic arteries and veins (the isolation procedure group) compared to a conventional procedure of transection of the splenic vein at the end.

Details
Condition Resectable Pancreatic Body/Tail Carcinoma, Resectable Pancreatic Body/Tail Carcinoma, Resectable Pancreatic Body/Tail Carcinoma
Treatment Isolation procedure (RAMPS procedure), Conventional procedure
Clinical Study IdentifierNCT04600063
SponsorWakayama Medical University
Last Modified on26 January 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Resectable pancreatic cancer (Adenocarcinoma, adenosquamous cell carcinoma, mucinous carcinoma, and anaplastic carcinoma according to the 7th edition of the regulations for handling pancreatic cancer)
ASA-PS (American Society of Anesthesiology, General condition classification) is Class 1-3
Age are over 20 years old
Able to understand the content of the research and has obtained written consent from the person himself/herself

Exclusion Criteria

Non-resectable pancreatic cancer by image diagnosis at the initial diagnosis
Cases suspected of portal vein (superior mesenteric vein) invasion
Patients with severe ischemic heart disease
Patients with cirrhosis or active hepatitis requiring treatment
Patients with dyspnea requiring oxygen administration
Patients undergoing dialysis due to chronic renal failure
Cases in which arterial reconstruction of the superior mesenteric artery, common hepatic artery, celiac artery, etc. is considered necessary
Patients with strong suspected paraaortic lymph node metastasis
Active double cancer thought to affect adverse events and prognosis
Long-term oral steroids that may affect adverse events
Patients who are considered to have difficulty participating in the study due to psychosis or psychiatric symptoms
Cases other than invasive pancreatic ductal carcinoma by preoperative biopsy. Invasive intraductal papillary mucinous carcinoma (IPMC) is excluded
Patients who cannot use both iodine drugs and gadnium drugs due to severe drug allergy
Cases where the prescribed procedure is difficult due to history of upper abdominal surgery such as stomach, spleen, kidney, liver, transverse colon, retroperitoneum including pancreas and pancreatitis
Clear my responses

How to participate?

Step 1 Connect with a site
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar
Name

Primary Contact

site
Name

0/250
Preferred Language
Other Language
Please verify that you are not a bot.

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Loading...

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 

 • 

Private

Reply by • Private
Loading...

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.
Loading...

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note