Study of Alemtuzumab to Treat Advanced Mycosis Fungoides/Sezary Syndrome

  • participants needed
  • sponsor
    Latin American Cooperative Onco-Haematology Group - Peru
Updated on 7 November 2020
sezary syndrome
renal function test
mycosis fungoides and sezary syndrome


The investigators designed a compassionate basis phase II study for refractory/relapsed mycosis fungoides/Sezary syndrome consisting of alemtuzumab (Campath) for primary evaluation of overall response and time to relapse. Other goals to consider are toxicity and time to new therapy.


- 20 relapsed or refractory advanced mycosis fungoides/Sezary syndrome patients are scheduled with gradually escalated doses (3 mg, 10 mg , and 30 mg) on sequential days during the first week, followed by 30 mg three times a week until 12 weeks. - Patients must have serology negative for human T-lymphotropic virus 1 (HTLV-1) and until three different regimens of chemotherapy. - Follow up for one year after last cycle of alemtuzumab.

Condition Mycosis Fungoides, Sezary Syndrome
Treatment alemtuzumab
Clinical Study IdentifierNCT00157274
SponsorLatin American Cooperative Onco-Haematology Group - Peru
Last Modified on7 November 2020


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