The Molecular Imaging Research of F-18 Labeled DX600 PET Probe

  • STATUS
    Recruiting
  • participants needed
    100
  • sponsor
    Beijing Cancer Hospital
Updated on 6 December 2022
Accepts healthy volunteers

Summary

Angiotensin-converting enzyme 2 (ACE2) plays an important role in renin-angiotensin system (RAS) and has been reported to relate with cancer. Recently, it has also been proved as the key target for COVID-19 infection.

DX600 is a polypeptide that can specific binding to ACE2 specifically with nanomolar affinity reported in literature. This study constrcuted a radio-tracer, DX600 Labeled by PET Radionuclide, to monitoring biodistribution ACE2 in human beings, evaluate the detection ability of radio-tracer in ACE2 over-expression tumors and dynamic changes of ACE2 expression under therapy.

Details
Condition Solid Tumor
Treatment 18F-DX600 PET/CT
Clinical Study IdentifierNCT04542863
SponsorBeijing Cancer Hospital
Last Modified on6 December 2022

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