The Effectiveness and Safety of FK-506 for the Treatment of Posner-Schlossman Syndrome

  • participants needed
  • sponsor
    Peking University
Updated on 15 October 2021


To evaluate the effectiveness and safety of tacrolimus eye drops (FK-506) in the treatment of Posner-Schlossman Syndrome. It is expected to collect 30 patients with PSS who are in the Ophthalmology Department of Peking University Third Hospital. The included PSS patients were divided into experimental group and control group using simple randomization method. Among them, the experimental group was treated with FK-506 twice a day, and the control group was treated with prednisolone acetate ophthalmic suspension 1% 4 times a day.

For all PSS patients whose intraocular pressure is higher than 30mmHg, also add brinzolamide eye drops 3 times a day. Best corrected visual acuity, Goldmann intraocular pressure, anterior section photographs, corneal endothelial cellscorneal confocal microscope, Heidelberg retinal nerve analysis, Octopus visual field were examined on baseline and 1 week, 2 weeks, 3 weeks, 4 weeks after the treatment.

Condition Posner Schlossman Syndrome
Treatment Prednisolone Acetate 1% Oph Susp, FK-506 (Drug)
Clinical Study IdentifierNCT04590183
SponsorPeking University
Last Modified on15 October 2021

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