A Study of V937 in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Solid Tumors (V937-013)

  • STATUS
    Not Recruiting
  • End date
    Jun 27, 2025
  • participants needed
    185
  • sponsor
    Merck Sharp & Dohme LLC
Updated on 8 August 2022
cancer
measurable disease
carcinoma
breast cancer
growth factor
x-rays
metastasis
fluoropyrimidine
pembrolizumab
epidermal growth factor receptor
HER2
EGFR
pd-l1
trastuzumab
sorafenib
adenocarcinoma
solid tumor
metastatic solid tumor
stage iv breast cancer
solid neoplasm
hepatitis b antigen
triple-negative breast cancer

Summary

The purpose of this study is to evaluate the safety, tolerability, and efficacy in participants with advanced/metastatic or recurrent malignancies who receive V937 in Combination with Pembrolizumab (MK-3475). The primary objective for Part 1 is to evaluate the objective response rate, and the primary objective for Part 2 is to determine the safety and tolerability of V937 administered in combination with pembrolizumab.

Details
Condition Neoplasm Metastasis
Treatment Pembrolizumab, V937
Clinical Study IdentifierNCT04521621
SponsorMerck Sharp & Dohme LLC
Last Modified on8 August 2022

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