Association Between Genetic Variant Scores and P2Y12 Inhibitor Effects

  • STATUS
    Recruiting
  • participants needed
    200
  • sponsor
    Cipherome, Inc.
Updated on 29 January 2022
myocardial infarction
infarct
ticagrelor
clopidogrel
prasugrel

Summary

The goal of this study is to predict and prevent adverse drug events by investigating the impact of genetic variants, demographics, and environmental factors in subjects status post myocardial infarction and percutaneous coronary insertion who have experienced adverse drug events while on P2Y12 inhibitors.

Description

The goal of this study it to validate Cipherome's drug safety score (DSS) in its predictive accuracy for severe adverse drug reactions (ADRs). The DSS is calculated on a scale of 0 to 1, with preliminary studies demonstrating that scores below 0.3 correlated with a higher chance of an ADR and scores above 0.7 correlated with a lower chance of an ADR.

Details
Condition heart attacks, myocardial infarction (mi), Heart Attack (Myocardial Infarction), Ischemic Stroke, cardiac infarction, myocardial necrosis, Stent Thrombosis, heart attack, Cardiac Ischemia, acute coronary syndromes, Myocardial Infarction, Acute Coronary Syndrome, Ischemic Heart Disease, Myocardial Ischemia
Clinical Study IdentifierNCT04580602
SponsorCipherome, Inc.
Last Modified on29 January 2022

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