Liposomal Bupivacaine vs Bupivacaine for Pain Control After Sternotomy

  • days left to enroll
  • participants needed
  • sponsor
    University of Kansas Medical Center
Updated on 25 January 2021


Researchers hope to learn whether giving the longer-acting local anesthetic liposomal bupivacaine prior to closing the sternum is more effective in managing pain following sternotomy, than in patients who received standard bupivacaine before sternal closure. Researchers will measure this based on how much IV pain medication is used, rates on confusion, and time to remove the breathing tube.

Condition Sternotomy, Analgesia, pain management, pain control, pain relieving, managed pain, pain therapy
Treatment Bupivacaine, Exparel
Clinical Study IdentifierNCT04585867
SponsorUniversity of Kansas Medical Center
Last Modified on25 January 2021


Yes No Not Sure

Inclusion Criteria

Adults over the age of 18 who present for elective open heart surgery that requires a sternotomy

Exclusion Criteria

Urgent and emergency procedures
preexisting sternal infections
prior sternotomy
preexisting pain syndromes
current chronic home opioid use
anterior rib or sternal masses
allergy to any of the components of liposomal bupivacaine and plain bupivacaine
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