Multi-dose Ibuprofen Prophylaxis for IUD-insertion

  • participants needed
  • sponsor
    Orlando VA Medical Center
Updated on 25 June 2022


This study compares the effectiveness of decreasing pain at time of and day after intrauterine device (IUD) insertion when patients take three doses of Ibuprofen versus three doses of placebo.


Ibuprofen is commonly used over the counter and prescribed for pain relief such as menstrual cramps. Intrauterine (IUD) insertion can cause pain during and after the insertion. Currently, studies have found that single dose of Ibuprofen take prior to IUD insertion does decrease pain at time of IUD insertion. This study will examine whether 3 doses of Ibuprofen can decrease pain at time of and 1 day after IUD insertion.

Condition Fetal Death, Pelvic Pain, Pain, Post-Surgical Pain, Pain (Pediatric), Pain, Intrauterine Device, Intrauterine Device, Post-Surgical Pain, Pain (Pediatric), female pelvic pain, intrauterine fetal demise, intrauterine fetal death, fetal demise
Treatment placebos, ibuprofen
Clinical Study IdentifierNCT03868137
SponsorOrlando VA Medical Center
Last Modified on25 June 2022

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