Effective Postoperative Pain Relief After Laparoscopic Cholecystectomy With TENS

  • STATUS
    Recruiting
  • End date
    Mar 25, 2024
  • participants needed
    166
  • sponsor
    Göteborg University
Updated on 25 January 2021
anesthesia
opioid
pain relief
cholecystectomy
postoperative pain relief

Summary

The study evaluates the effect of TENS (transcutaneous electrical nerve stimulation) treatment for first line of treatment compared with conventional treatment with opioids on pain relief and time spent time in the post-anesthesia care unit after laparoscopic cholecystectomy. Half of the patients are randomized to TENS as first line of treatment and the second half is randomized to conventional opioid treatment. Patients who does not report postoperative pain which requires treatment are used as controls.

Description

Postoperative pain is often a problem after laparoscopic cholecystectomy. Conventional treatment with intravenous (iv) opioids often offers satisfactory pain relief. However, opioids have negative side effects, such as sedation, nausea, and respiratory depression. Some of these side effects require monitoring of the patient, resulting in longer duration of stay in the post-anesthesia care unit (PACU) after surgery. Transcutaneous electrical nerve stimulation (TENS) has been used to provide pain relief in various postoperative pain conditions. Previous studies from the investigator's center indicate that TENS treatment for postoperative pain after gynecological surgery results in shorter time in the PACU.

Previous studies indicate that patients reporting pain intensity associated with venous cannulation to > 2 VAS (visual analog scale) units have higher risk of postoperative pain in the PACU. The aim of the study is to compare time spent in the PACU and to compare the postoperative pain relieving effect of high frequency, high intensity TENS as first line of treatment with conventional treatment with iv opioids in patients undergoing laparoscopic cholecystectomy. Furthermore, the study evaluates if postoperative opioid consumption can be reduced by using TENS as first line of treatment. In addition, the study tests if pain intensity associated with venous cannulation can be used to predict occurrence of postoperative pain.

Details
Condition Postoperative pain, post-operative pain, post-op pain
Treatment TENS (transcutaneous electrical nerve stimulation), iv opioid
Clinical Study IdentifierNCT04114149
SponsorGöteborg University
Last Modified on25 January 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

For randomized patients
Patients who reports postoperative pain intensity 3 according to numeric
rating scale during the stay in the post-anesthesia care unit after
laparoscopic cholecystectomy
For controls
Patients who reports postoperative pain intensity <3 according to numeric
rating scale during the stay in the post-anesthesia care unit after
laparoscopic cholecystectomy

Exclusion Criteria

(for all patients)
Patients who do not want to participate in the study
Patients younger than 18 years
Inadequate knowledge of the Swedish language
Patients with pacemaker or internal cardioverter defibrillator
Patients who preoperatively report continuous opioid consumption
Patients with chronic pain conditions
Patients with impaired sensibility over the dermatomes that are to be treated with TENS
Alcohol or substance abuse
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