Prospective Evaluation of Biliary Tissue Sampling With ERCP

  • End date
    May 30, 2026
  • participants needed
  • sponsor
    Mayo Clinic
Updated on 9 December 2021


The purpose of this study is to assess the safety, outcomes and performance characteristics of multiple biliary sampling techniques including but not limited to: single operator cholangioscopy (SOC) directed biopsies, transpapillary biliary biopsies (TPBx), brushings and bile aspiration for cytology and FISH in patients undergoing ERCP.

Condition Adenocarcinoma, Biliary Stricture, Cholangiocarcinoma, Endoscopic Retrograde Cholangiopancreatography, Biliary tract disease, Malignant Adenoma
Clinical Study IdentifierNCT04572711
SponsorMayo Clinic
Last Modified on9 December 2021


Yes No Not Sure

Inclusion Criteria

Adults > 18 years
Diagnosis of indeterminate biliary stricture
Scheduled clinically indicated ERCP procedure

Exclusion Criteria

Adults <18 years, Children
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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