Dendritic Cell Immunotherapy Plus Standard Treatment of Advanced Renal Cell Carcinoma

  • End date
    Mar 26, 2022
  • participants needed
  • sponsor
Updated on 26 January 2021


CMN-001 is an autologous, tumor antigen-loaded dendritic cell immunotherapy. The active components of CMN-001 are autologous, matured dendritic cells, which have been co-electroporated with both in vitro transcribed (IVT) RNA from an autologous tumor specimen and CD40L RNA. CMN-001 is indicated for treatment of intermediate/poor risk patients with advanced renal cell carcinoma (RCC) in combination with nivolumab plus ipilimumab as first line therapy and in combination with lenvatinib plus everolimus as 2nd line therapy post 1st line failure.

Condition Advanced Renal Cell Carcinoma
Treatment Nivolumab+Ipilimumab, CMN-001, Lenvatinib+Everolimus
Clinical Study IdentifierNCT04203901
Last Modified on26 January 2021


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