Palonosetron and Blood Coagulation

  • End date
    Dec 15, 2022
  • participants needed
  • sponsor
    Seoul National University Bundang Hospital
Updated on 23 April 2022
Accepts healthy volunteers


Palonosetron may alter whole blood coagulation. However, little is known about the dose-response relationships according to the blood concentration of palonosetron. The investigators therefore will perform the present study to measure the effect of palonosetron levels using thromboelastography.

Condition Blood Coagulation Disorder
Treatment 0 ul of palonosetron, 0.2 ul of palonosetron, 2.0 ul of palonosetron, 4 ul of palonosetron, 1 ul of palonosetron, 10 ul of palonosetron, 100 ul of palonosetron
Clinical Study IdentifierNCT04507711
SponsorSeoul National University Bundang Hospital
Last Modified on23 April 2022


Yes No Not Sure

Inclusion Criteria

Healthy volunteers
Age: 20 to 65 years
Body weight > 50 kg
Volunteers who provided informed consent

Exclusion Criteria

Hematologic disease
Anticoagulant medication
Clear my responses

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