Imaging With [89Zr]Panitumumab-PET/MRI in Patients With Newly Diagnosed Colorectal Cancer

  • STATUS
    Recruiting
  • End date
    Jan 25, 2026
  • participants needed
    10
  • sponsor
    University of Alabama at Birmingham
Updated on 25 January 2021
cancer
EGFR

Summary

This clinical study will investigate the utility of PET imaging with [89Zr]Panitumumab for imaging of EGFR expression in newly diagnosed colon cancer patients to assess lymph node involvement. If promising, this data will be used to design larger trials.

Details
Condition Metastatic Colon Cancer
Treatment [89Zr]Panitumumab PET-MRI
Clinical Study IdentifierNCT03764137
SponsorUniversity of Alabama at Birmingham
Last Modified on25 January 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Is your age greater than or equal to 19 yrs?
Gender: Male or Female
Do you have Metastatic Colon Cancer?
Do you have any of these conditions: Do you have Metastatic Colon Cancer??
Be at least 19 years of age
Diagnosis of colon cancer
Scheduled to undergo surgical resection

Exclusion Criteria

Inability to provide informed consent
Pregnancy
Inability to lie still for the imaging study
Weight over 350 lbs., due to the scanner bore size
Contraindication for MRI study (e.g. non-removable metal implants or certain tattoos)
Inability to receive Omnipaque (iohexol) iodinated contrast
Inability to receive glucagon
Inability to receive Eovist (gadoxetate disodium) gadolinium based contrast agent
Allergy to contrast imaging agents
Finding or suspicion of distant metastases on CT
Clear my responses

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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