Imaging With [89Zr]Panitumumab-PET/MRI in Patients With Newly Diagnosed Colorectal Cancer

  • End date
    Jan 20, 2026
  • participants needed
  • sponsor
    University of Alabama at Birmingham
Updated on 20 October 2021


This clinical study will investigate the utility of PET imaging with [89Zr]Panitumumab for imaging of EGFR expression in newly diagnosed colon cancer patients to assess lymph node involvement. If promising, this data will be used to design larger trials.

Condition Metastatic Colon Cancer
Treatment [89Zr]Panitumumab PET-MRI
Clinical Study IdentifierNCT03764137
SponsorUniversity of Alabama at Birmingham
Last Modified on20 October 2021


Yes No Not Sure

Inclusion Criteria

Be at least 19 years of age
Diagnosis of colon cancer
Scheduled to undergo surgical resection

Exclusion Criteria

Inability to provide informed consent
Inability to lie still for the imaging study
Weight over 350 lbs., due to the scanner bore size
Contraindication for MRI study (e.g. non-removable metal implants or certain tattoos)
Inability to receive Omnipaque (iohexol) iodinated contrast
Inability to receive glucagon
Inability to receive Eovist (gadoxetate disodium) gadolinium based contrast agent
Allergy to contrast imaging agents
Finding or suspicion of distant metastases on CT
Clear my responses

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Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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