Hydromorphone for ICU-analgesia in Patients With Non-mechanical Ventilation

  • days left to enroll
  • participants needed
  • sponsor
    Nanfang Hospital of Southern Medical University
Updated on 23 March 2022


Hydromorphone has a clear analgesic effect, and has few advantages in respiratory depression and gastrointestinal motility. The study will further explore the continuous pumping-dose of hydromorphone for ICU non-mechanical ventilation patients and monitor its effective plasma concentration as well as evaluates the safety and effectiveness of hydromorphone for ICU non-mechanical ventilation patients.

Condition Hydromorphone, Analgesia, ICU
Treatment Fentanyl, Hydromorphone, Butorphanol
Clinical Study IdentifierNCT04436224
SponsorNanfang Hospital of Southern Medical University
Last Modified on23 March 2022


Yes No Not Sure

Inclusion Criteria

Age ≥18 years old
Non-mechanical ventilation patients with expected ICU stay time >24h
People with moderate to severe pain who need immediate analgesic treatment (NRS ≥ 4 or BPS ≥ 5 points, CPOT ≥ 3)

Exclusion Criteria

can not get pain score from patients
allergy to drugs
Clear my responses

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