Detecting Chemosensitivity and Predicting Treatmemt Efficacy With CTCs in mNPC

  • STATUS
    Recruiting
  • days left to enroll
    63
  • participants needed
    50
  • sponsor
    Sun Yat-sen University
Updated on 20 August 2021
carcinoma
fluorouracil
iv infusion
metastasis
gemcitabine
chemotherapy regimen
docetaxel
administration intravenous
mnpc

Summary

The prospective observational clinical study will recruit 50 metastatic nasopharyngeal carcinoma (mNPC) patients, detecting patient's chemosensitivity with the circulating tumor cells (CTCs) from peripheral blood and prdicting patient's treatment efficacy with CTCs dynamic change.

Details
Condition Advanced Malignancies, Liver Metastases, Metastatic Cancer, Nasopharyngeal Cancer, Metastasis, Effects of Chemotherapy, Vulvar Dysplasia and Carcinoma, Neoplasm Metastasis, Distant Metastases.Clinical, Carcinoma, Tumor embolus, Brain Metastases, Bone Metastases, nasopharyngeal carcinoma
Treatment cisplatin-based chemotherapy
Clinical Study IdentifierNCT04544969
SponsorSun Yat-sen University
Last Modified on20 August 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

NPC patients with distant metastasis after 3 months of primary radiotherapy, and not suitable for local treatment
At least having one measurable metastatic lesion
All gendersrange from 1870 years old
ECOG score 0 ~ 1
Expected survival time 3 months
White blood cell(WBC) count 3109/L, neutrophile granulocyte(NE) count 1.5109/L, hemoglobin(HGB) 90g/L, platelet(PLT) count 100109/L
Alanine aminotransferase (ALT) or aspartate aminotransferase(AST) < 2.5upper limit of normal(ULN), bilirubin(BUN) or creatinine(CRE) < 1.5ULN, alanine aminotransferase (CCR) 60ml/min
Inform consent form

Exclusion Criteria

Have or are suffering from other malignant tumors
Participating in other clinical trials
Drug or alcohol addition
Do not have full capacity for civil acts
Mental disorder
Pregnancy or lactation
Severe complication, eg, uncontrolled hypertension
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

0/250

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Loading...

Browse trials for

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 

 • 

Private

Reply by • Private
Loading...

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.
Loading...

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note