GM1 in the Treatment of Neurotoxicity Induced by Albumin-bound Paclitaxel

  • participants needed
  • sponsor
    Henan Cancer Hospital
Updated on 27 September 2022


Taxane-induced peripheral neuropathy (TIPN) caused by albumin-bound paclitaxel is a dose-limiting toxicity. The main symptoms of discomfort are numbness, tingling, and burning sensations in the glove-sock-like distribution of the limbs. At present, there are few effective methods for clinical treatment of TIPN, and there is no widely agreed consensus on effective treatment in the world. Therefore, it is of great clinical significance and practical value to carry out clinical research to explore drugs to relieve TIPN.

Condition Early Breast Cancer
Treatment Placebo, monosialic gangliosides
Clinical Study IdentifierNCT04538833
SponsorHenan Cancer Hospital
Last Modified on27 September 2022

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