Exercise is Medicine: a Cohort Study

  • End date
    Nov 30, 2024
  • participants needed
  • sponsor
    Chinese University of Hong Kong
Updated on 27 January 2021


6,000 patients with HT and/or DM will be recruited to participate a 12-week EIM exercise intervention, which also involve consistent feedback and reminders using information technology (IT). The primary outcome will be improvement of blood pressure at 1-year. Other clinical outcomes will be obtained on recruitment (baseline), 12-week (immediately after EIM classes) and 1-year after recruitment

Condition Vascular Diseases, Vascular Diseases, Hypertension, High Blood Pressure (Hypertension), High Blood Pressure (Hypertension - Pediatric), Diabetes and Hypertension, Diabetes and Hypertension, High Blood Pressure (Hypertension), High Blood Pressure (Hypertension - Pediatric), Elevated Blood Pressure, high blood pressure, arterial hypertension
Treatment exercise is medicine
Clinical Study IdentifierNCT04249557
SponsorChinese University of Hong Kong
Last Modified on27 January 2021


Yes No Not Sure

Inclusion Criteria

have a clinical diagnosis of primary HT and/or type II DM from clinical medical record
having less than 150 minutes of moderate intensity exercise per week OR having less than 75 minutes of intensive intensity exercise per week (this is set according to latest World Health Organization guideline)
who have used any mobile apps on their phone (because the intervention involve use of apps to monitor and remind regular exercise)

Exclusion Criteria

patients with diagnosed chronic obstructive lung disease and recent stroke (within last 12 months)
Patients on 3 or more anti-hypertensive medications (on maximum or maximal tolerable doses) are excluded because these patients have resistant HT and may represent another spectrum of disease
Patients with spinal cord compression, radiculopathy with active pain, or osteoarthritis of hips and knees that are on the waiting list for joint replacement surgery are excluded for safety reasons
acute myocardial infarction in last 6 months
ongoing angina
uncontrolled cardiac arrhythmia
acute diseases including known active endocarditis/acute pulmonary embolism, pulmonary infarction, deep vein thrombosis, acute aortic dissection, acute myocarditis
known aortic stenosis
known heart failure
known obstructive left main coronary artery stenosis
uncontrolled ventricular rates
complete heart block
known hypertrophic obstructive cardiomyopathy
mental impairment that limit co-operation
resting blood pressure with systolic blood pressure >180mmHg or diastolic blood pressure >110mmHg
known anaemia with haemoglobin level less than 11gm/dL
known uncorrected electrolyte imbalance
known uncontrolled hyperthyroidism
For DM patients, patients with proliferative diabetic retinopathy and recent retinal bleeding (in last 12 months)
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