Evaluating a new cognitive test for people with neurologic conditions

Updated on 16 May 2021


Cerebellar cognitive affective syndrome (CCAS) is a pattern of cognitive changes that can result from cerebellar injury or disease. CCAS can involve impairment of planning, abstract reasoning, working memory, and visuospatial processing as well as language difficulties and personality changes. The CCAS can be identified in patients with cerebellar disorders by a new scale, the CCAS / Schmahmann Scale. The specific aim of this study is to determine whether this new scale can distinguish between patients with cerebellar disorders and those with other neurodegenerative conditions.


The current cognitive tests in wide clinical use are not effective at determining the cognitive impairments seen in CCAS. You can help us identify whether this new scale is the best test for detecting this condition in comparison to current cognitive tests. Our first goal is to determine whether the CCAS scale can identify cognitive profiles that distinguish cerebellar patients from those with other neurodegenerative conditions. Our second goal is to determine whether the CCAS scale is a more sensitive screening tool than current tests for detection of cognitive change in a range of neurological disorders.

Condition Alzheimer's Disease, Mild Cognitive Impairment, *Healthy Volunteers
Clinical Study IdentifierTX251283
Last Modified on16 May 2021

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