A Pilot Study of Empagliflozin in the Treatment of Acromegalic Cardiomyopathy

  • STATUS
    Recruiting
  • participants needed
    10
  • sponsor
    Huashan Hospital
Updated on 4 October 2022
insulin
heart failure
pituitary
somatostatin
growth hormone
adenoma
insulin-like growth factor
growth factor
cardiomyopathy

Summary

Acromegaly is a disease characterized by excess growth hormone(GH) and insulin like growth factor(IGF)-1. Pituitary GH secreting adenoma is the major cause of acromegaly. Acromegalic cardiomyopathy is one of the leading causes of death in acromegalic patients. No efficient medicine is available for acromegalic cardiomyopathy until now and there were limited studies. Empagliflozin is proved to decrease the risk of heart failure in diabetic patients and independent of blood glucose control. We planed to evaluate the structure of heart by MRI before and after 6 months treatment with empagliflozin in acromegalic patients to investigate the effect of empagliflozin on acromegalic cardiomyopathy.

Details
Condition Acromegaly, Acromegaly, Heart disease, Heart disease, Cardiac Disease, Cardiomyopathy, Cardiomyopathy, Cardiac Disease, cardiomyopathies, myocardial diseases
Treatment Empagliflozin
Clinical Study IdentifierNCT04520646
SponsorHuashan Hospital
Last Modified on4 October 2022

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