A Pilot Study of Empagliflozin in the Treatment of Acromegalic Cardiomyopathy

  • participants needed
  • sponsor
    Huashan Hospital
Updated on 4 October 2022
heart failure
growth hormone
insulin-like growth factor
growth factor


Acromegaly is a disease characterized by excess growth hormone(GH) and insulin like growth factor(IGF)-1. Pituitary GH secreting adenoma is the major cause of acromegaly. Acromegalic cardiomyopathy is one of the leading causes of death in acromegalic patients. No efficient medicine is available for acromegalic cardiomyopathy until now and there were limited studies. Empagliflozin is proved to decrease the risk of heart failure in diabetic patients and independent of blood glucose control. We planed to evaluate the structure of heart by MRI before and after 6 months treatment with empagliflozin in acromegalic patients to investigate the effect of empagliflozin on acromegalic cardiomyopathy.

Condition Acromegaly, Acromegaly, Heart disease, Heart disease, Cardiac Disease, Cardiomyopathy, Cardiomyopathy, Cardiac Disease, cardiomyopathies, myocardial diseases
Treatment Empagliflozin
Clinical Study IdentifierNCT04520646
SponsorHuashan Hospital
Last Modified on4 October 2022

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