Bowel Colonization With Multi-drug Resistant Bacterial Species in Hospitalized Patients With acute-on Chronic Liver Failure (ACLF) and Its Relationship With Extra-intestinal Infectious Events and Short-term Outcomes.

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    Institute of Liver and Biliary Sciences, India
Updated on 25 January 2022


Bowel colonization with anti-microbial resistant bacteria increases the risk of clinical infections. Infections caused by anti-microbial resistant bacteria have been associated with increased mortality, prolonged hospital stay, and increased costs. In addition, with the emergence of carbapenemase resistant bacterial species, there may not be any effective therapy for patients infected with such resistant species.

Bowel colonization with anti-microbial resistant bacteria is an established risk factor for infections due to resistant bacteria, especially in transplanted patients and in intensive care unit. In this study we will study whether bowel colonisation in Acute on Chronic Liver Failure patient increases the risk of infection development in extra intestinal sites.

Condition Acute on Chronic Liver Failure
Treatment No intervention
Clinical Study IdentifierNCT04383106
SponsorInstitute of Liver and Biliary Sciences, India
Last Modified on25 January 2022

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