Different Limb Lengths in Gastric Bypass Surgery
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- STATUS
- Recruiting
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- End date
- Dec 31, 2026
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- participants needed
- 800
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- sponsor
- Clarunis - Universitäres Bauchzentrum Basel
Summary
Obesity and type 2 diabetes mellitus (T2DM) are reaching epidemic proportions in the developed world. In morbidly obese patients only surgical treatment (bariatric operations) leads to a sustained weight loss and relief of co-morbidities in the majority of patients. One of the most frequently performed operations is the laparoscopic proximal Roux-en-Y gastric bypass (LRYGB). There is still lack of knowledge why some patients respond much better than others to an identically performed procedure. Therefore, a number of variations of this operation have been introduced over the past 50 years. Increasing the length of small bowel being bypassed has the potential to improve the effect of the operation but buries the risk of nutrient deficiencies. The metabolic effect of LRYGB occurs, in part, independently of weight loss. The mechanisms underlying metabolic improvement through metabolic surgery are not yet fully understood.
Details
| Condition | Morbid obesity, NIDDM, Diabetes Mellitus, Type 2, Diabetes Mellitus Type 2, Vascular Diseases, Vascular Diseases, Hypertension, High Blood Pressure (Hypertension), High Blood Pressure (Hypertension - Pediatric), Diabetes and Hypertension, Dyslipidemia, Dyslipidemia, Sleep apnea, Sleep Apnea Syndromes, Diabetes Mellitus, Type 2, Diabetes and Hypertension, High Blood Pressure (Hypertension), High Blood Pressure (Hypertension - Pediatric), Elevated Blood Pressure, Sleep Apnea Syndromes, Diabetes Mellitus Type 2, type 2 diabetes mellitus, severe obesity, high blood pressure, arterial hypertension, type 2 diabetes, type ii diabetes, noninsulin-dependent diabetes mellitus, diabetes type 2 |
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| Treatment | Long BPL LRYGB, Short BPL LRYGB |
| Clinical Study Identifier | NCT04219787 |
| Sponsor | Clarunis - Universitäres Bauchzentrum Basel |
| Last Modified on | 25 January 2021 |
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