Different Limb Lengths in Gastric Bypass Surgery

  • End date
    Dec 31, 2026
  • participants needed
  • sponsor
    Clarunis - Universitäres Bauchzentrum Basel
Updated on 25 January 2021
type 2 diabetes mellitus
bypass surgery
bariatric surgery
gastric bypass
obesity surgery


Obesity and type 2 diabetes mellitus (T2DM) are reaching epidemic proportions in the developed world. In morbidly obese patients only surgical treatment (bariatric operations) leads to a sustained weight loss and relief of co-morbidities in the majority of patients. One of the most frequently performed operations is the laparoscopic proximal Roux-en-Y gastric bypass (LRYGB). There is still lack of knowledge why some patients respond much better than others to an identically performed procedure. Therefore, a number of variations of this operation have been introduced over the past 50 years. Increasing the length of small bowel being bypassed has the potential to improve the effect of the operation but buries the risk of nutrient deficiencies. The metabolic effect of LRYGB occurs, in part, independently of weight loss. The mechanisms underlying metabolic improvement through metabolic surgery are not yet fully understood.

Condition Morbid obesity, NIDDM, Diabetes Mellitus, Type 2, Diabetes Mellitus Type 2, Vascular Diseases, Vascular Diseases, Hypertension, High Blood Pressure (Hypertension), High Blood Pressure (Hypertension - Pediatric), Diabetes and Hypertension, Dyslipidemia, Dyslipidemia, Sleep apnea, Sleep Apnea Syndromes, Diabetes Mellitus, Type 2, Diabetes and Hypertension, High Blood Pressure (Hypertension), High Blood Pressure (Hypertension - Pediatric), Elevated Blood Pressure, Sleep Apnea Syndromes, Diabetes Mellitus Type 2, type 2 diabetes mellitus, severe obesity, high blood pressure, arterial hypertension, type 2 diabetes, type ii diabetes, noninsulin-dependent diabetes mellitus, diabetes type 2
Treatment Long BPL LRYGB, Short BPL LRYGB
Clinical Study IdentifierNCT04219787
SponsorClarunis - Universitäres Bauchzentrum Basel
Last Modified on25 January 2021


Yes No Not Sure

Inclusion Criteria

patients with BMI of 35 kg/m2 or higher who comply with the regulatory rules for bariatric surgery in Switzerland (SMOB guidelines)

Exclusion Criteria

general contraindications to kind of surgery
known or suspected non-compliance, drug or alcohol abuse
inability to follow the procedures of the study, e.g. due to language problems, psychological disorders etc. of the participant
participation in another study
age < 18 years or > 65 years
BMI > 60 kg/m2
height < 145 cm
CL length of < 180 cm as measured intraoperatively
ASA physical status classification > III
inflammatory bowel disease
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