This is a Phase III, randomized, parallel-arm, placebo controlled, double blind, multicenter study assessing the efficacy and safety of durvalumab versus placebo following SoC chemotherapy in patients with completely resected stage II-III NSCLC who are MRD+ post surgery
Patients who have no evidence of disease recurrence confirmed by CT and/or MRI and are confirmed to meet all eligibility criteria will be randomized 1:1 to durvalumab + Standard of care (SoC) chemotherapy or placebo + Standard of care (SoC) chemotherapy arm.
The primary objective of this study is to assess the efficacy of durvalumab +SoC chemotherapy compared to placebo+ SoC chemotherapy in terms of DFS measured in MRD+ patients.
Condition | Carcinoma, Non-Small-Cell Lung |
---|---|
Treatment | Durvalumab + SoC chemotherapy, Placebo + SoC chemotherapy |
Clinical Study Identifier | NCT04385368 |
Sponsor | AstraZeneca |
Last Modified on | 8 August 2022 |
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