Azacitidine and Homoharringtonine in JMML
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- STATUS
- Recruiting
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- End date
- Jan 1, 2025
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- participants needed
- 30
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- sponsor
- Air Force Military Medical University, China
Summary
Juvenile myelomonocytic leukemia (JMML) has a poor prognosis in general, with hematopoietic stem cell transplant (HSCT) remaining the standard of care for cure. Azacitidine and homoharringtonine, which exhibited a anticancer mechanism and has been widely used in patients with relapse/refractory acute myeloid leukemia (AML). However, the efficacy of these agents has not been elucidated in children with JMML. The primary objective is to assess the treatment effect on response rate in this subject population.
Details
| Condition | Juvenile Myelomonocytic Leukemia |
|---|---|
| Treatment | Azacitidine and homoharringtonine |
| Clinical Study Identifier | NCT04505995 |
| Sponsor | Air Force Military Medical University, China |
| Last Modified on | 25 January 2021 |
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