Hyperventilation in Patients With Chronic Low Back Pain

  • End date
    Aug 25, 2022
  • participants needed
  • sponsor
    Hasselt University
Updated on 25 January 2021
back pain


Low back pain (LBP) is the leading cause of disability worldwide. Impaired postural control is a key factor in the development and maintenance of LBP. Moreover, the prevalence of LBP is associated with impairments in diaphragm function, symptoms of dyspnea, and dysfunctional breathing. However, the association between LBP (and more specifically postural control) and hyperventilation remains unknown. The main objective of this project is to investigate whether the presence of recurrent non-specific LBP is related to the presence of hyperventilation, when classified either objectively by decreased carbon dioxide values (demonstrating hypocapnia) or by symptoms while showing normal carbon dioxide values. Moreover, the investigators will explore whether psychosocial factors play a role in this relation. Subsequently, the investigators will examine whether hyperventilation in LBP patients is related to impaired postural control, and more specifically to a decreased postural contribution of the diaphragm.

Condition Low Back Pain, Lower Back Pain, Hyperventilation Syndrome, Lower Back Pain
Treatment assessment of hyperventilation, postural control and psychological behavior
Clinical Study IdentifierNCT04074798
SponsorHasselt University
Last Modified on25 January 2021


Yes No Not Sure

Inclusion Criteria

Chronic primary low back pain (>12 weeks) as diagnosed by a medical doctor
Inclusion Criteria Healthy controls
No low back pain

Exclusion Criteria

Insufficient understanding of Dutch language
Previous spinal surgery
Chronic Obstructive Lung Disease, Interstitial Lung Disease, pulmonary vascular disease, asthma except for exertional asthma
Acute cardiovascular or gastrointestinal disorders
Neuromuscular disease interfering with normal lower limb or trunk functioning
Acute pain or secondary chronic pain
Pregnant and lactating women
Major psychiatric conditions
Acute lower limb problems
Vestibular disorders
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