Measurement of Myocardial Stiffness Using Elastometry in Patients With Aortic Stenosis

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  • sponsor
    University Hospital, Rouen
Updated on 21 September 2023
coronary artery bypass graft
aortic valve replacement
left ventricular remodeling


Elastography is a new non-invasive medical technique for measuring the stiffness at a distance from a tissue. Recent advances in the development of elastography sequences for cardiac exploration suggest a more clinical approach to cardiac elastography. This study propose to compare myocardial stiffness of a group of coronary bypass patients without hypertrophic left ventricular remodeling or sequelae of myocardial infarction versus a group of patients who should benefit from a surgical aortic valve replacement for aortic stenosis.

The hypothesis is that the physiological adaptation to pressure overload constituted by aortic stenosis is responsible for a significant increase in myocardial stiffness compared to a reference group.

Condition VALVULAR HEART DISEASE, aortic valve stenosis, Aortic Stenosis, Heart Valve Disease
Treatment Aixplorer Mach30
Clinical Study IdentifierNCT04358692
SponsorUniversity Hospital, Rouen
Last Modified on21 September 2023

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