A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Crinecerfont (NBI-74788) in Adult Subjects With Classic Congenital Adrenal Hyperplasia, Followed by Open-Label Treatment (CAHtalyst)

  • STATUS
    Not Recruiting
  • End date
    Feb 18, 2024
  • participants needed
    165
  • sponsor
    Neurocrine Biosciences
Updated on 25 August 2023
deficiency
21-ohd

Summary

This is a Phase 3 study to evaluate the efficacy, safety, and tolerability of crinecerfont versus placebo administered for 24 weeks in approximately 165 adult subjects with classic CAH due to 21-hydroxylase deficiency. The study consists of a 6 month randomized, double blind, placebo-controlled period, followed by 1 year of treatment with crinecerfont. Duration of participation is approximately 20 months.

Details
Condition Congenital Adrenal Hyperplasia
Treatment Placebo, Crinecerfont
Clinical Study IdentifierNCT04490915
SponsorNeurocrine Biosciences
Last Modified on25 August 2023

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