Central Arterial Pressure Changes With Use of Regional Anesthesia in Obstetric Patients

  • End date
    Dec 28, 2025
  • participants needed
  • sponsor
    St. Louis University
Updated on 4 October 2022
Accepts healthy volunteers


Plan to monitor central arterial pressure in women who are undergoing spinal anesthesia for cesarean delivery or epidural anesthesia for vaginal delivery.


Subjects will be screened as they are admitted to the maternity care floor (5th floor St. Mary's Hospital). Subjects will be approached if they are desiring regional anesthesia.

The subject will have an additional blood pressure cuff placed on the arm that anesthesia is not using for their blood pressure cuff. Central arterial pressure will be measured from the

  • Prior to regional anesthesia placement
  • Every 15 minutes for 1 hour
  • Every 30 minutes for 2 hours Routine sphygmomanometer measurements will also completed at the above times. These are all study procedures.

Anesthesia will use their usual protocol for blood pressure monitoring and management during placement of, and after the procedure. No changes in patient management will be made based upon the central arterial pressure as the guidelines were developed with routine brachial pressure.

Condition Central Blood Pressures
Clinical Study IdentifierNCT02933541
SponsorSt. Louis University
Last Modified on4 October 2022


Yes No Not Sure

Inclusion Criteria

Singleton pregnancy
Planned regional anesthesia

Exclusion Criteria

Multiple pregnancy
Emergent cesarean delivery
Irregular heart rhythms or arrhythmias
Peripheral arterial disease, leg artery disease
Reynaud's phenomena
Intense cold/hypothermia
If there is a wound at location of where central arterial cuff would be placed or tonometer for carotid assessment
Severe tachycardia (>120)
Greater than 1st degree heart block
Congestive heart failure or heart disease
Inability to adequately monitor BP
Use of magnesium sulfate
Clear my responses

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