Instrumental Activities of Daily Living Study

Updated on 15 September 2020
early diagnosis


This study is looking for people over the age of 65 years who have mild memory problems. The study is interested in whether computer-based memory tests can help to make an early diagnosis of Alzheimer’s disease.


Study schedule:
At the start of the study:
-You will have a computerized memory test.
-You will answer questions about your daily activities.
-You will have brain scans (described below).
-You will wear a small device that tracks the number of steps you walk.
During the study:
-You will repeat the study-start activities.
-In all, you will visit the clinic eight times over three years.
The study will end after about three years.

Study activities may include:
-Completing a memory test and answering questions about your daily activities. These will be via computerized questionnaires.
-Wearing a device to track the number of steps you walk.
-Having brain scans (described below).
-Having an injection as a standard part of the brain scan procedure.

Treatment or experiment details:
-One of the brain scans is an MRI. For this, you will lie inside the scanning machine for about an hour while it takes a 3D image of your brain.
-The other brain scan is a PET scan. For this, you will have an injection in your arm vein. Then, you will lie inside the scanning machine for about an hour while it takes a 3D image of your brain.
-There is no treatment being tested in this study. The study is interested in the progression of memory problems over time.

Condition Alzheimer's Disease, Alzheimer's Disease, Mild Cognitive Impairment, Memory Problems, *Healthy Volunteers
Clinical Study IdentifierTX249081
Last Modified on15 September 2020


Yes No Not Sure

Inclusion Criteria

You could be eligible for this study if
You are between 60 to 90 years of age
You are generally in good health
You have mild memory problems
You have access to a smartphone or a tablet
You have a ‘study partner’—a family member, friend, spouse, or caregiver—who would be willing to answer questions about you
You may not be eligible for this study if
You cannot have an MRI scan, for example because of metal in your body
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How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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