The Subjective Cognitive Decline Cohort Study

  • STATUS
    Recruiting
Updated on 15 September 2020

Summary

This study is looking for people over the age of 60 who have memory concerns. The study is interested in whether memory concerns will later develop into Alzheimer’s or cognitive decline.

Description

Study schedule
At the start of the study:
-You will complete memory assessments.
-You will answer questions about your mood and behavior.
-You and your study partner will complete online questionnaires every three months.
-You will have brain scans (described below).
During the study:
-You will repeat some or all of the study-start activities.
-You will visit the site nine times over a period of three years.
The study will end after about three years.

Study activities may include:
-Having a memory screening and answering questions about your mood and behavior. This will be in the form of interview-style conversations, paper-and-pencil questionnaires, computer tests, and/or other activities.
-Completing online questionnaires.
-Having brain scans (described below).
-Having an injection as a standard part of the brain scan procedure.

Treatment or experiment details:
-One of the brain scans is an MRI. For this, you will lie inside the scanning machine for about an hour while it takes a 3D image of your brain. There will be a total of two MRI scans during the study.
-The other brain scan is a PET scan. For this, you will have an injection in your arm vein. Then, you will lie inside the scanning machine for about an hour while it takes a 3D image of your brain. There will be a total of three PET scans during the study.
-There is no treatment being tested in this study. The study is interested in in whether memory concerns will later develop into Alzheimer’s or cognitive decline.

Details
Condition Memory Problems
Clinical Study IdentifierTX249080
Last Modified on15 September 2020

Eligibility

Yes No Not Sure

Inclusion Criteria

You could be eligible for this study if
You are between the age of 60 and 90 years old
You have memory concerns, as confirmed by study-start testing
You have a ‘study partner’- a family member, friend, or caregiver- who would be willing to answer questions about you
You and your study partner have access to the internet and can use a computer
You may not be eligible for this study if
You cannot have an MRI, for example because of metal in your body
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How to participate?

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What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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