A Novel Multimodality MRI Biomarker of Asymptomatic Alzheimer’s Disease.

Updated on 24 January 2022
Accepts healthy volunteers


This study is looking for people over the age of 55 who have mild cognitive impairment. The study is also looking for people with normal cognition, as a comparison. The study is testing a new kind of brain scan for diagnosing early-stage Alzheimer’s.


Study schedule: -All study activities will be done in a single visit that is 4-5 hours long. If necessary, it can be split into two shorter visits. Study activities may include: -Doing cognitive assessments, via paper-and-pencil questionnaires and computer tasks. -Giving a sample of saliva. -Having a brain scan (described below). Treatment or experiment details: -The brain scan is an MRI. For this, you will lie inside the scanning machine for about an hour while it takes a 3D image of your brain. -There is no treatment or experiment being tested in this study. Additional details: -It is preferred that participants who have mild cognitive impairment are accompanied by another adult.

Condition Mild Cognitive Impairment, *Healthy Volunteers
Clinical Study IdentifierTX249068
Last Modified on24 January 2022


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Inclusion Criteria

You could be eligible for this study if: -You are between the ages of 55 and 80. -You either: Have mild cognitive impairment; or Are cognitively normal. You may not be eligible for this study if: -You have severe high blood pressure, diabetes, or a major psychiatric illness. -You take anti-anxiety medications on a regular basis. -You cannot have an MRI, for example because of metal in your body
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How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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