The Therapeutic Value and Mechanism of Recombinant Human Interleukin-2 in Children With Henoch-sch nlein Purpura
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- STATUS
- Recruiting
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- End date
- Dec 31, 2022
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- participants needed
- 60
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- sponsor
- The First Hospital of Jilin University
Summary
The study aims to explore the therapeutic value and mechanism of Interleukin-2 on children with Henoch-schnlein purpura.
Description
The investigators designed a single center, open-label, prospective study that routinely administered low-dose IL-2 therapy to monitor the improvement of clinical and laboratory parameters to explore its efficacy and to observe changes in immune cell subsets and cytokines.For all patients,rhIL-2(500,000 unit per square meter) infusions seven days;recurrent patients were applied again for 7 days;patients who were diagnosed HSPN were treated on a routine basis for 7 consecutive days, and then once every two week for 3months.
Details
| Condition | Allergic Purpura |
|---|---|
| Treatment | IL-2 |
| Clinical Study Identifier | NCT04387942 |
| Sponsor | The First Hospital of Jilin University |
| Last Modified on | 22 October 2021 |
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