Qualitative and Quantitative Evaluation of Vascular Flows of Radial Ulnar and Interdigital Arterial Trees Under Normal and Pathological Conditions by 3 Tesla MRI

  • End date
    Mar 27, 2029
  • participants needed
  • sponsor
    Centre Hospitalier Universitaire, Amiens
Updated on 27 January 2021
doppler ultrasound


Allotransplants of vascularized composite tissues are subject to chronic vascular rejection, which can lead to graft loss. Currently, no imaging technique allows a reproducible quantitative exploration of the arterial trees of the hand, and therefore a satisfactory monitoring of transplants. Since 2014, flow MRI has been applied to the analysis of small-calibre arteries by the Image Processing Team at the Amiens-Picardie University Hospital. Between 2015 and 2017, several acquisitions were made in 3 patients who received facial allotransplantation, and the team recently developed a flow MRI protocol dedicated to the study of arterial trees in the hand.

The main objective is to measure vascular flows of radial, ulnar and interdigital arterial trees in normal (healthy volunteers) and pathological situations (patients with radial forearm flap reconstruction and patients with hand allotransplantation) using the specifically developed flow MRI protocol.

Condition grafts, Transplantation, Magnetic Resonance Imaging, Organ Transplantation, Radial Artery, Organ Transplant - Pediatric, Organ Transplant, Vascular Complications, grafting procedure, transplant procedure
Treatment MRI acquisitions, Doppler ultrasound procedure
Clinical Study IdentifierNCT04257747
SponsorCentre Hospitalier Universitaire, Amiens
Last Modified on27 January 2021


Yes No Not Sure

Inclusion Criteria

Adult ( 18 years old)
patients who has received appropriate information and provided informed consent
patients benefiting from social security insurance
patients with no contraindications to magnetic resonance imaging
healthy volunteer or patient requiring radial forearm flap reconstruction or having received hand allotransplantation

Exclusion Criteria

Person with a contraindication to MRI
pregnant or breastfeeding woman
minors (< 18 years)
person under guardianship or deprived of liberty by a judicial or administrative decision
person with upper limb arteriopathy with the exception of the hand transplant patients group
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