A Multicenter, acute, randomized, double-blind, placebo-controlled, flexible-dose trial with
the treatment of sertraline.
Randomized, double-blind, placebo-controlled trial of an evidence-based antidepressant,
sertraline, in youth (N=120) with generalized, separation and/or social anxiety disorders,
seeks to evaluate the predictive value of plasma EV signatures. Patients will be randomized
to sertraline (25-200 mg/day) or placebo (3:1) and total plasma EVs will be collected at
baseline and serially during the course of the 12-week treatment period.
If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.
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