Memory and Aging Project

  • STATUS
    Recruiting
Updated on 25 February 2022
Accepts healthy volunteers

Summary

This study is looking for two groups of healthy people over 65: those who have memory loss and those who are cognitively normal. The study will collect data every year to learn about the aging process.

Description

Study schedule:
Over several study visits, participants will complete all of the following:
-Have a medical exam (2.5 hours).
-Do cognitive testing (2 hours).
-Give a blood sample.
-Give a spinal fluid sample.
-Have brain scans (1 hour, each; described below).
Study activities will be repeated yearly. This study is longitudinal (continuing over time).

Study activities may include:
-Having a medical exam. It will be focused on memory and physical health concerns.
-Doing cognitive testing, which may be in the form of interview-style conversations, paper-and-pencil questionnaires, computer tests, and/or other activities.
-Having a sample of blood taken from your arm vein, using a needle.
-Having a sample of spinal fluid drawn from your lower back (spine), using a needle. This is also known as a lumbar puncture or a spinal tap.
-Having brain scans (described below).
-Having an injection as a standard part of the brain scan procedure.

Treatment or experiment details:
-One of the brain scans is an MRI. For this, you will lie inside the scanning machine for about an hour while it takes a 3D image of your brain.
-The other brain scan is a PET scan. For this, you will have an injection in your arm vein and then lie inside the scanning machine for about an hour while it takes a 3D image of your brain.
-There is no treatment or experiment being tested in this study. It is intended to learn about the aging process. This may be used to develop better ways to diagnose and treat Alzheimer’s.

Additional details:
-Some participants may be offered participation in other study activities, such as sleep assessments. These activities are optional.



Details
Condition Mild Cognitive Impairment,*Healthy Volunteers, Memory Loss
Clinical Study IdentifierTX248762
Last Modified on25 February 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

You could be eligible for this study if
You are 65 or older
You are generally healthy
You have a ‘study partner’—a family member, friend, or caregiver—who would be willing to answer questions about you
You either
Have memory loss; or
Have normal cognition
You may not be eligible for this study if
You do not meet all entry criteria, as determined by screening questions
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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