Middle Aged Offspring of Parents with Late Alzheimer's Disease

Updated on 31 May 2022
Accepts healthy volunteers


This study is looking for people between the ages of 35 and 59 who have a parent with Alzheimer’s. The study is also looking for people who do not have a family history of Alzheimer’s, as a comparison. The study is interested in the relationship between cognitive function, brain health, and family history of Alzheimer’s.


Study schedule: 
-The study requires one or two visits to the study center.
-You will have a basic medical exam.
-You will give a blood sample.
-You will answer questions about your health.
-You will have a cognitive assessment. It will take about four hours.
-You will have a brain scan (described below).

Study activities may include:
-Having a medical exam.
-Having a sample of blood drawn from your arm vein, using a needle.
-Answering questions about your health and having a cognitive assessment. This may be in the form of interview-style conversations, paper-and-pencil questionnaires, computer tests, and/or other activities.
-Having a brain scan (described below).

Treatment or experiment details: 
-The brain scan is an MRI. For this, you will lie inside the scanning machine for about an hour while it takes a 3D image of your brain.
-There is no treatment being tested in this study.
-The study is interested in the relationship between cognitive function, brain health, and family history of Alzheimer’s.

Additional details:
-Your blood sample will be used, among other things, for genetic testing.

Condition Alzheimer's Disease, Alzheimer's Disease, *Healthy Volunteers
Clinical Study IdentifierTX248759
Last Modified on31 May 2022


How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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