Nutrition in Gastrointestinal Tumors

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    University Medicine Greifswald
Updated on 9 November 2021
cancer chemotherapy
gastrointestinal cancer
cytostatic drugs
gastrointestinal tumor


Malnutrition and loss of muscle mass frequently occur in patients undergoing chemotherapy and can negatively effect therapy outcome. Especially patients with cancer of the gastrointestinal tract are often affected by malnutrition. Therefore, this study aims to examine changes in nutritional status of patients with cancer of the gastrointestinal tract during chemotherapy. Findings of this study will help to improve nutritional treatment of patients undergoing chemotherapy.


Malnutrition and sarcopenia are common complications in patients with malignant diseases of the gastrointestinal tract. During chemotherapy there is a high risk of further impairment of nutritional status due to anorexia, nausea, emesis and other gastrointestinal conditions that adversely impact food assimilation or absorption. Findings on changes of nutritional status during chemotherapy are scarce but of paramount importance for adequate nutrition therapy. Therefore, this study aims to provide a detailed description of changes in nutritional status of patients with a malignant condition of the gastrointestinal tract during chemotherapy.

Condition Digestive System Neoplasms, Gastropathy, pancreatic cancers, Bile duct carcinoma, Colon Cancer, cancer, hepatocellular, Liver Cancer, cancer, liver, gastric cancers, cancer, pancreatic, cancer of the bile duct, Stomach Cancer, cancer of the pancreas, Esophageal Cancer, Pancreatic Cancer, gastrointestinal stromal tumor, Gastric Carcinoma, oesophageal cancer, Colorectal Cancer, liver cancers, Pancreatic Disorders, Gastric Cancer, Biliary neoplasm, Malignant neoplasm of colon, small intestinal cancer, Colon Cancer Screening, Neoplasm of unspecified nature of digestive system, Urothelial Tract Cancer, Rectal Cancer, HEPATIC NEOPLASM, Colon cancer; rectal cancer, colon carcinoma, Neurectoderma, Islet Ce417ll Cancer, Cholangiocarcinoma, Small Intestine Cancer, esophagus cancer, Neuroectodermal Tumor, Biliary Tract Cancer, rectal carcinoma, cancer, hepatic, Stomach Discomfort, Neuroendocrine Tumor, neuroendocrine tumour, Pancreatic disorder, neuroendocrine tumors
Treatment No intervention - observational study only
Clinical Study IdentifierNCT04476082
SponsorUniversity Medicine Greifswald
Last Modified on9 November 2021


Yes No Not Sure

Inclusion Criteria

Patients with initial diagnosis of a malignant condition of the gastrointestinal tract planned to receive cytostatic treatment
ongoing cytostatic treatment of a known malignant condition of the gastrointestinal tract

Exclusion Criteria

history of any other malignant tumor disease
inability to provide consent
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