Outcomes of RV Dysfunction in Acute Exacerbation of Chronic Respiratory Diseases

  • STATUS
    Recruiting
  • days left to enroll
    44
  • participants needed
    40
  • sponsor
    Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Updated on 31 July 2021
COPD
mechanical ventilation
troponin
pro-brain natriuretic peptide
respiratory failure
acute respiratory failure
pulmonary disease
neuromuscular diseases
hypoventilation
obstructive lung disease
bronchiectasis
assisted ventilation
respiratory disease

Summary

Observational study in patients with chronic respiratory diseases (chronic obstructive pulmonary diseases, bronchiectasis, interstitial lung diseases, neuromuscular diseases, obesity-hypoventilation syndrome...) admitted in intensive care unit for acute respiratory failure. The main objective is to determine the prevalence of right ventricular (RV) dysfunction in this population and to analyze the impact of such a complication on outcomes (survival at day-28, duration of non-invasive or mechanical ventilation, duration of hospital stay). RV function will be assessed by echocardiography at admission, after 3 days and at discharge. Plasma NT-proBNP and troponin levels will be collected.

Description

Observational study in patients with chronic respiratory diseases (chronic obstructive pulmonary diseases, bronchiectasis, interstitial lung diseases, neuromuscular diseases, obesity-hypoventilation syndrome...) admitted in intensive care unit for acute respiratory failure.

Inclusion Criteria:

  • Chronic respiratory disease (COPD, ILD, OHS...)
  • Admission in ICU for acute respiratory failure
  • Patient's non-opposition

Exclusion Criteria:

  • Patients < 18 year-old
  • Protected patients
  • Pregnant women The main objective is to determine the prevalence of right ventricular (RV) dysfunction in this population and to analyze the impact of such a complication on outcomes (survival at day-28, duration of non-invasive or mechanical ventilation, duration of hospital stay). RV function will be assessed by echocardiography at admission, after 3 days and at discharge. Plasma NT-proBNP and troponin levels will be collected.

Details
Condition Pulmonary Disease, Amyotonia Congenita, nervous system disorder, Pulmonary Fibrosis, Obesity, Pickwickian Syndrome, Interstitial lung disease, Acute Respiratory Failure, Acute Exacerbation of Bronchiectasis, Acute Exacerbation of COPD, Asthma Attack, Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Neurologic Disorders, Lung Disease, Acute Exacerbation of Asthma, neuromuscular diseases, obesity hypoventilation syndrome, interstitial lung diseases, neuromuscular disorders, neuromuscular disease, neuromuscular disorder, acute copd exacerbations
Clinical Study IdentifierNCT04098094
SponsorAssociation pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Last Modified on31 July 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Chronic respiratory disease (COPD, ILD, OHS...)
Admission in ICU for acute respiratory failure
Patient's non-opposition

Exclusion Criteria

Patients < 18 year-old
Protected patients
Pregnant women
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