Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S

  • STATUS
    Not Recruiting
  • days left to enroll
    6
  • participants needed
    50
  • sponsor
    Quadriga Biosciences, Inc.
Updated on 10 October 2022
renal function
cancer
measurable disease
carcinoma
kidney function tests
thymus cancer
astrocytoma
solid tumor
sarcoma
cholangiocarcinoma
kidney function test
thymic carcinoma
cancer, thymic

Summary

This is a multi-center, open-label, dose escalation study to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, and maximum tolerated dose (MTD) of QBS10072S in patients with advanced or metastatic cancers with high LAT1 expression. The MTD of QBS10072S will be confirmed in patients with relapsed or refractory grade 4 astrocytoma.

Details
Condition Astrocytoma, Brain Cancer, Brain Metastases, Bladder Cancer, Breast Cancer, Cervical Cancer, Cholangiocarcinoma, Colorectal Cancer, Esophagus Cancer, Gastric Cancer, Head and Neck Cancer, Kidney Cancer, Liver Cancer, Lung Cancer, Melanoma, Ovarian Cancer, Pancreatic Cancer, Pleural Mesothelioma, Prostate Cancer, Sarcoma, Tongue Cancer, Thymic Carcinoma, Urinary Tract Cancer
Treatment QBS10072S
Clinical Study IdentifierNCT04430842
SponsorQuadriga Biosciences, Inc.
Last Modified on10 October 2022

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