Brentuximab Vedotin Plus Lenalidomide and Rituximab for the Treatment of Relapsed/Refractory DLBCL (ECHELON-3)
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- STATUS
- Recruiting
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- End date
- Apr 30, 2027
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- participants needed
- 400
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- sponsor
- Seagen Inc.
Summary
Participants in this study will have diffuse large B-cell lymphoma (DLBCL) that has come back or not gotten better with treatment. The trial will study whether brentuximab vedotin plus two drugs works better to treat this type of cancer than the two drugs alone.
Participants will be randomly assigned to get either brentuximab vedotin or placebo. The placebo will look like brentuximab vedotin, but has no medicine in it. Since the study is "blinded," participants and their doctors will not know whether a participant gets brentuximab vedotin or placebo. All participants in the study will get rituximab and lenalidomide. These are drugs that can be used to treat DLBCL.
Details
| Condition | Diffuse Large B-cell Lymphoma |
|---|---|
| Treatment | Rituximab, Placebo, Lenalidomide, brentuximab vedotin |
| Clinical Study Identifier | NCT04404283 |
| Sponsor | Seagen Inc. |
| Last Modified on | 11 April 2023 |
Eligibility
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.
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