A Study of Hydroxychloroquine Vitamin C Vitamin D and Zinc for the Prevention of COVID-19 Infection

  • STATUS
    Recruiting
  • End date
    Jul 27, 2025
  • participants needed
    600
  • sponsor
    ProgenaBiome
Updated on 27 October 2021
vitamin d
covid-19
hydroxychloroquine
zinc
Accepts healthy volunteers

Summary

This is a Phase II interventional study testing whether treatment with hydroxychloroquine, Vitamin C, Vitamin D, and Zinc can prevent symptoms of COVID-19

Description

In this study, subjects will take a regimen of hydroxychloroquine, vitamin C, vitamin D, and Zinc to test if this combination can prevent COVID-19. Treatment with hydroxychlorquine will last 1 day. Treatment with vitamin C, vitamin D, and and zinc will last 12 weeks. The study will last 12 weeks.

Details
Condition Severe Coronavirus Disease (COVID-19), Covid-19, Hospitalized Patients With Covid-19 Pneumonia, SARS-CoV-2 (COVID-19) Infection, Coronavirus Disease (COVID-19), Treat and Prevent Covid-19 Infection, Old Age, Usability, Visio Telephony, Confinement, Covid-19, *COVID-19 Infection, Coronavirus Infection, *Corona Virus Infection, Pathogen Infection Covid-19 Infection, COVID-19 Infection, Coronavirus, Corona Virus Disease 2019(COVID-19), Acute Respiratory Distress Syndrome Caused by COVID-19, SARS COV2, COVID-19 Pneumonia, Use of Stem Cells for COVID-19 Treatment, COVID-19, Hydroxychloroquine Sulfate, Anxiety Related to the COVID-19 Pandemic, Corona Virus Infection, Coronavirus 19, Sars-CoV2, COVID-19 by SARS-CoV-2 Infection, Community-acquired Pneumonia, Influenza, COVID-19, COVID-19, COVID-19; Cardiovascular Diseases, *COVID-19
Treatment Vitamin C, zinc, hydroxychloroquine, Vitamin D
Clinical Study IdentifierNCT04335084
SponsorProgenaBiome
Last Modified on27 October 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Informed consent, provided electronically via the EDC, demonstrating the subject understands the procedures required for the study and the purpose of the study
Male or female patients 18 years of age or older that are considered to be high-risk individuals
High-risk individuals are defined as all health care workers in hospitals, clinics, and emergency rooms, and medical facilities
Subjects must agree to practice at least two highly effective methods of birth control for the duration of the study This includes condoms with spermicide, oral birth control pills, contraceptive implants, intra-uterine devices, or diaphragms. At least one of these must be a barrier method. Subjects not of reproductive potential will be exempt (e.g. post-menopausal, surgically sterilized)

Exclusion Criteria

Refusal to provide informed consent
Any previous positive test for COVID-19 by RT-PCR
Symptomatic for COVID-19
Diarrhea prior to the start of treatment
Type I or II diabetes
Atherosclerotic Coronary Artery Disease
Any contraindication for treatment with hydroxychloroquine including
Hypoglycemia
G6PD deficiency
Porphyria
Anemia
Neutropenia
Alcoholism
Myasthenia Gravis
Skeletal muscle disorder
Maculopathy
Changes in the visual field
Liver disease, with ALT/AST > 2.5 upper limit normal and total bilirubin >2.5 upper limit normal
Psoriasis
Any contraindicated medications found in Appendix 2
Any comorbidities which, in the opinion of the investigator, constitute health risk for the subject
Vaccination for SARS-CoV-2
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

0/250

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Loading...

Browse trials for

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 

 • 

Private

Reply by • Private
Loading...

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.
Loading...

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note