Antler Plate on Preventing Mammary High-risk Lesions From Malignant Development

  • End date
    Jun 25, 2025
  • participants needed
  • sponsor
    Jilin University
Updated on 25 January 2021


This study aims to prove whether antler disk extract can be put into clinical practice to prevent breast precancerous lesions from developing into cancer.


Through estrogen receptor antagonists, tamoxifen can reduce the risk of breast high-risk disease progression to cancer, but only reduce the probability of some ER and PR positive tumors, which has no preventive effect on triple negative breast cancer and HER-2 positive breast cancer. In the first hospital of Jilin University, the preparations containing antler ingredients have been clinically proven to be able to treat breast hyperplasia, which has been proved to be able to prevent breast cancer in basic research, and antler ingredients have been proved to be non-toxic and side effects in the treatment dose. This study aims to prove whether antler disk extract can be put into clinical practice to prevent breast precancerous lesions from developing into cancer.

Condition Breast Cancer Prevention
Clinical Study IdentifierNCT04440683
SponsorJilin University
Last Modified on25 January 2021


Yes No Not Sure

Inclusion Criteria

Women between the ages of 18 and 80
Atypical hyperplasia or / and lobular carcinoma in situ confirmed by breast histology
Women with breast cancer in first degree relatives
Patients have better compliance with a series of research-related behaviors such as the upcoming comprehensive treatment and follow-up, and can understand and accept the research process of this study, and sign a written informed consent

Exclusion Criteria

Hepatorenal dysfunction, cardiovascular and cerebrovascular diseases
Patients not suitable for this study judged by researchers
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